The study - conducted in nonhuman primates with brain structures and functions similar to those of humans - found that the antidepressant sertraline, a selective serotonin reuptake inhibitor (SSRI) marketed as Zoloft, significantly increased the volume of one brain region in depressed subjects but decreased the volume of two brain areas in non-depressed subjects. "These observations are important for human health because Zoloft is widely prescribed for a number of disorders other than depression," said Carol A. D., professor of pathology-comparative medicine at Wake Forest Baptist and lead author of the study, published in the current online issue of the journal Neuropharmacology. In the study, 41 middle-aged female monkeys were fed a diet formulated to replicate that consumed by many Americans for 18 months, during which time depressive behavior in the animals was recorded. Female monkeys were chosen for this study because depression is nearly twice as common in women as men and the use of antidepressants is most common in women ages 40 to 59. After the 18-month pre-study phase, the monkeys were divided into two groups balanced for body weight, body mass index and depressive behavior. For the next 18 months, 21 monkeys received sertraline in daily doses comparable to those taken by humans while a group of 20 received a placebo. This treatment regimen is analogous to a human taking an antidepressant for approximately five years. Manish K Singh, MD Assistant Professor, Department of Neurology, Teaching Faculty for Pain Management and Neurology Residency Program, Hahnemann University Hospital, Drexel College of Medicine; Medical Director, Neurology and Pain Management, Jersey Institute of Neuroscience Manish K Singh, MD is a member of the following medical societies: American Academy of Neurology, American Academy of Pain Medicine, American Headache Society, American Association of Physicians of Indian Origin, American Medical Association, American Society of Regional Anesthesia and Pain Medicine Disclosure: Nothing to disclose. Francisco Talavera, Pharm D, Ph D Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference Disclosure: Received salary from Medscape for employment. Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS Professor Emeritus of Neurology and Psychiatry, Clinical Professor of Medicine, Clinical Professor of Family Medicine, Clinical Professor of Neurosurgery, State University of New York Upstate Medical University; Neuroscience Director, Department of Neurology, Crouse Irving Memorial Hospital Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS is a member of the following medical societies: American College of International Physicians, American Heart Association, American Stroke Association, American Academy of Neurology, American Academy of Pain Medicine, American College of Forensic Examiners Institute, National Association of Managed Care Physicians, American College of Physicians, Royal College of Physicians, Royal College of Physicians and Surgeons of Canada, Royal College of Surgeons of England, Royal Society of Medicine Disclosure: Nothing to disclose. Joseph Carcione, Jr, DO, MBA Consultant in Neurology and Medical Acupuncture, Medical Management and Organizational Consulting, Central Westchester Neuromuscular Care, PC; Medical Director, Oxford Health Plans Joseph Carcione, Jr, DO, MBA is a member of the following medical societies: American Academy of Neurology Disclosure: Nothing to disclose.
The antidepressant Zoloft (sertraline) is sometimes prescribed to treat people who have frequent tension headaches or migraines. However, its effectiveness at treating headaches varies. Since this drug can cause side effects, you should discuss the potential risks and benefits of taking Zoloft with your doctor. I started taking 50mg sertraline almost a week ago for anxiety induced headaches and OCD. I started to get chronic headaches around mid October and after being referred to a neurologist, he diagnosed me with anxiety and prescribed me xanax to help deal with the headaches. He also scheduled an MRI just to be safe which turned out to be normal. The xanax helped a bit, but I decided I didn't want to become dependant and decided to seek a more long term solution to my anxiety. Went back to the neurologist and he prescribed me Zoloft. I was still having headaches and slight vision problems but after being on 50 mg for a couple days, I began having my usual chronic headaches accompanied by a strange sensation in my head when I breathed in. It's kind of like a rush of dull pain that intensifies as I breathe in. It's dizzying and unrelenting and seems to creep up on me as the day goes by, becoming the worst at night.
In fact, preclinical evidence suggests that Zoloft may prove efficacious as a treatment for tension-type headaches, regardless of comorbid. Viral gastroenteritis is an intestinal infection marked by watery diarrhea, abdominal cramps, nausea or vomiting, and sometimes fever. The most common way.