Gynecomastia (guy-nuh-koh-MAS-tee-uh) is swelling of the breast tissue in boys or men, caused by an imbalance of the hormones estrogen and testosterone. Gynecomastia can affect one or both breasts, sometimes unevenly. Newborns, boys going through puberty and older men may develop gynecomastia as a result of normal changes in hormone levels, though other causes also exist. Generally, gynecomastia isn't a serious problem, but it can be tough to cope with the condition. Gynecomastia is triggered by a decrease in the amount of the hormone testosterone compared with estrogen. Men and boys with gynecomastia sometimes have pain in their breasts and may feel embarrassed. The cause of this decrease can be conditions that block the effects of or reduce testosterone or a condition that increases your estrogen level. Several things can upset the hormone balance, including the following. The hormones testosterone and estrogen control the development and maintenance of sex characteristics in both men and women. Tamoxifen blocks the actions of estrogen, a female hormone. Certain types of breast cancer require estrogen to grow. Tamoxifen is used to treat some types of breast cancer in men and women. It is also used to lower a woman's chance of developing breast cancer if she has a high risk (such as a family history of breast cancer). Use a barrier form of birth control (such as a condom or diaphragm with spermicide) while you are using this medication and for at least 2 months after your treatment ends. Tamoxifen may also be used for purposes not listed in this medication guide. You should not use tamoxifen if you are allergic to it, or if you have a history of blood clots in your veins or your lungs, or if you are also taking a blood thinner such as warfarin (Coumadin). Before using this medicine, tell your doctor if you have liver disease, high triglycerides (a type of fat in the blood), a history of cataract, or a history of stroke or blood clot. Also tell your doctor if you if you are receiving chemotherapy or radiation treatment.
Will using nolvadex tamoxifen help reduce my pubertal gynecomastia? 2 doctors responded I'm 77, a male, diagnosed with gynecomastia, non-cancerous, tender lump size of walnut under one nipple. Gynecomastia may be treated with medications such as raloxifene Evista and tamoxifen Soltamox. The U. S. Food and Drug Administration FDA has approved these medications to treat breast cancer.