Sertraline is used for a number of conditions, including major depressive disorder (MDD), obsessive–compulsive disorder (OCD), body dysmorphic disorder (BDD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder, and social anxiety disorder (SAD). The comparative efficacy of sertraline and TCAs for melancholic depression has not been studied. A 1998 review suggested that, due to its pharmacology, sertraline may be more efficacious than other SSRIs and equal to TCAs for the treatment of melancholic depression. A meta-analysis of 12 new-generation antidepressants showed that sertraline and escitalopram are the best in terms of efficacy and acceptability in the acute-phase treatment of adults with unipolar MDD. Sertraline used for the treatment of depression in elderly (older than 60) patients was superior to placebo and comparable to another SSRI fluoxetine, and TCAs amitriptyline, nortriptyline (Pamelor) and imipramine. Sertraline had much lower rates of adverse effects than these TCAs, with the exception of nausea, which occurred more frequently with sertraline. In addition, sertraline appeared to be more effective than fluoxetine or nortriptyline in the older-than-70 subgroup. placebo in elderly patients showed a statistically significant (that is, unlikely to occur by chance), but clinically very modest improvement in depression and no improvement in quality of life. A meta-analysis on SSRIs and SNRIs that look at partial response (defined as at least a 50% reduction in depression score from baseline) found that sertraline, paroxetine and duloxetine were better than placebo. Summary Description and Clinical Pharmacology Indications and Dosage Warnings and Precautions Side Effects and Adverse Reactions Drug Interactions, Overdosage, Contraindications, Other Rx Info Active Ingredients User Ratings / Reviews Side Effect Reports Below are Zoloft (Sertraline) reviews, ratings, comments submitted by patients and caregivers. Based on a total of 52 ratings/reviews, Zoloft has an overall score of 7.56. The effectiveness score is 8 and the side effect score is 7.88. The scores are on ten point scale: 10 - best, 1 - worst. I had to slowly put myself into situations that previously made me very anxious, this drug truly helped!!! Completely eliminated anxiety disorder characterized by panic attacks and generalized anxiety after dosage of 50 mg/day was taken. This information is not vetted and should not be cosidered as clinical evidence. Downsside was that while on 25 mg/day start up dose for the first 7 days anxiety was extremely worsened and almost unbearable. While I definitely did notice some improvement in my depression, I believe that Zoloft is far from being a truly effective antidepressant drug. Patient taking 50 mg/day for generalized anxiety disorder and panic attacks. Anxiety extremely heightened and patient almost disscontinued med because of it. My depression had somewhat subsided and my panic attacks were less severe, albeit not completely gone. Hung in there and pill started to decrease and finally eliminate anxiety.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. Tocris products are intended for laboratory research use only, unless stated otherwise. Keywords: Sertraline hydrochloride, Sertraline hydrochloride supplier, 5-HT, reuptake, inhibitors, inhibits, Serotonin, Transporters, SERT, 5-Hydroxytryptamine, Monoamine, Neurotransmitter, Pfizer, ssri, 2395, Tocris Bioscience $50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today! *Please note that Tocris will only send literature to established scientific business / institute addresses. Hi guys, [smile]I asked this in the main 'Depression' forum and then only found this Sertraline forum afterwards so I thought I'd ask here. I've been on sertraline for two years and it's been a life saver for me but I've noticed the different brands have differing efficacy with me so I was wondering what company/brand you're all on and what you think of it? I believe the most common ones are Accord, Pfizer, Bristol and Dr Reddy's. Would be very interested to know what brands everyone is taking!
Fluphenazine, sold under the brand names Prolixin among others, is an antipsychotic medication. It is used in the treatment of chronic psychoses such as schizophrenia. Find user ratings and reviews for sertraline oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction