Propecia conception

By: 1maxik1 On: 05-Jan-2019
Finasteride - I see there are warnings not to take Finestride.

Finasteride - I see there are warnings not to take Finestride.

The quotes below are taken from the circular included with propecia tablets by manufacturers Merck. "Semen levels have been measured in 35 men taking finasteride 1 mg daily for 6 weeks. In 60% (21 of 35) of the samples, finasteride levels were undetectable. The mean finasteride level was 0.26 ng/m L and the highest level measured was 1.52 ng/m L. Using this highest semen level measured and assuming 100% absorption from a 5-m L ejaculate per day, human exposure through vaginal absorption would be up to 7.6 ng per day, which is 750 times lower than the exposure from the no-effect dose for developmental abnormalities in Rhesus monkeys." And; "No developmental abnormalities have been observed in first filial generation (F1) male or female offspring resulting from mating finasteride-treated male rats (80 mg/kg/day; 488 times the human exposure) with untreated females. Administration of finasteride at 3 mg/kg/day (150 times the recommended human dose of 1 mg/day) during the late gestation and lactation period resulted in slightly decreased fertility in F1 male offspring. No effects were seen in female offspring." And; "The in utero effects of finasteride exposure during the period of embryonic and fetal development were evaluated in the rhesus monkey (gestation days 20-100), a species more predictive of human development than rats or rabbits. Could there be a link between Finasteride and fertility? Finasteride, a drug used to prevent enlarged prostate glands as well as treat male pattern baldness, has been put under the microscope. The question is whether or not it decreases fertility. Studies argue that there's not a significant link between Finasteride and fertility. In the past, there have been concerns about sexual dysfunction as a result of taking Finasteride, a drug used as a preventative measure against benign prostatic hyperplasia (enlargement of the prostate gland) and, maybe eventually, prostate cancer (the FDA has still not approved the drug for prevention of prostate cancer). When weighing the benefits of preventing benign prostatic hyperplasia against the odds of causing sexual dysfunction, it's important to do your homework and consult with your doctor. Finasteride works by slowing down the enzyme that transforms testosterone into dihydrotestosterone.

FINASTERIDE Drug BNF content published by NICE
FINASTERIDE Drug BNF content published by NICE

Suicidal thoughts in men taking finasteride Propecia ® for male pattern hair loss; depression is also associated with Proscar. Conception and contraception. PROPECIA® finasteride, a synthetic 4-azasteroid compound, is a specific. PROPECIA tablets for oral administration are film-coated tablets that contain 1 mg.

Propecia conception
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